Baculovirus Expression Systems

Product name:Baculovirus Expression Systems

Product Description:The Baculovirus Expression Vector System (BEVS) has been widely used in research and scientific industrial communities for the production of high levels (up to 1000mg/mL) of properly post-translationally modified (folding, disulfide bond formation, oligomerization, glycosylation, acylation, proteolytic cleavage), biologically active and functional recombinant proteins. The Baculovirus Expression Vector System is based on the introduction of a foreign gene into nonessential for viral replication genome region via of homologous recombination with a transfer vector containing target gene. The resulting recombinant Baculovirus lacks one of nonessential gene (polh, v-cath, chiA etc.) replaced with foreign gene encoding heterologous protein which can be expressed in cultured insect cells and insect larvae. Baculovirus Facility in Cambridge offers services on protein expression and production - from recombinant baculovirus production to large scale protein expression.