Rho(D) immune globulin

Produc Name:Rho(D) immune globulin
Product Description:Rho(D) Immune Globulin is a medicine given by intramuscular injection that is used to prevent the immunological condition known as Rhesus disease (or hemolytic disease of newborn). The medicine is a solution of IgG anti-D (anti-RhD) antibodies that bind to, and lead to the destruction of, fetal Rh D positive red blood cells that have passed from the fetal circulation to the maternal circulation. Therefore, in a Rhesus negative mother it can prevent sensitization of the maternal immune system to Rh D antigens, which can cause rhesus disease in the current or in subsequent pregnancies. With the widespread use of Rho(D) Immune Globulin, Rh disease of the fetus and newborn has almost disappeared.
Use:
The medication has an FDA Pregnancy Category C. It is given by intramuscular injection as part of modern routine antenatal care at about 28 weeks of pregnancy, and within 72 hours after childbirth. It is also given after antenatal pathological events that are likely to cause a feto-maternal hemorrhage.
Infused Rho(D) has also been used with some success in treating chronic idiopathic thrombocytopenic purpura in Rh-positive patients who have not been splenectomized. The exact process by which Rho(D) counteracts the destruction of platelets is not fully understood.