Total T4

Product name:Total T4

Descriptions:The thyroid gland produces T4, trilodothyronine T3 and calcitonin. The first two hormones are synthesized by the gland following entrapment of iodine, conversion to iodine, and coupling of iodine with tyrosine, followed by coupling of two iodinated tyrosine molecules. T4 and T3 so formed are attached to thyroglobulin for storage and are released, as needed, as protease splits them from the globulin. Thyroxine is a highly active thyrometabolic hormone, which exists, in protein-bound and unbound forms. For T4 can be measured more easily and with greater accuracy than T3, determination of total T4 by immunoassay is the most reliable and convenient screening test available for detecting thyroid disorders in man.