Vinorelbine Tartrate

Product name:Vinorelbine Tartrate
Cas No.: 125317-39-7
Formula: C49H60N4O14
Mol Weight: 929.033
Appearance: white to off-white crystalline powder
Density: 1.36g/cm3
Melting Point: 181-183°C
Storage Temperature: 2-8°C
Refractive index: 1.675
Solubility: 10 mg/mL in water
Biological Activity: Selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. Inhibits proliferation of multiple human tumor cell lines (IC 50 = 1.25 nM in HeLa cells) and blocks metaphase/anaphase transition by suppression of microtubule dynamics (IC 50 = 3.8 nM). Reduces spindle length by 29% and inhibits microtubule polymerization at micromolar concentrations.
Usage: An antineoplastic