β-hydroxy β-methylbutyrate (HMB)

Product Name : β-hydroxy β-methylbutyrate (HMB)

Product Description :
β-Hydroxy β-methylbutyric acid (HMB), or β-hydroxy β-methylbutyrate, is a metabolite of the essential amino acid leucine and is synthesized in the human body. It plays a part in protein synthesis. It has been used in scientific studies to purportedly increase muscle mass and decrease muscle breakdown. It was discovered in pigs and small quantities can also be found in grapefruit, alfalfa, and catfish. As a supplement it is usually sold as a calcium salt.HMB may have an effect on increasing muscle weight and strength. A review in Nutrition &

HMBs proposed mechanisms of action the following:
1.Increased sarcolemmal integrity via conversion to HMG-CoA
2.Enhanced protein synthesis via the mTOR pathway
3.Depression of protein degradation through inhibition of the ubiquitin pathway