Aprepitant

Product name : Aprepitant

CAS : 170729-80-3

Molecular formula : C₂₃H₂₁F₇N₄O₃ 

Molecular Weight : 534.4266624

Product description :
Aprepitant (Emend (US, EU)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA). It mediates its effect by blocking the neurokinin 1 (NK1) receptor.Aprepitant is manufactured by Merck & Co. under the brand name Emend for prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) and for prevention of postoperative nausea and vomiting. It was approved by the FDA in 2003.Aprepitant may also be useful in the treatment of cyclic vomiting syndrome but there are few studies to date.