Corticosterone

Product name: Corticosterone
Synonym: 11β,21-Dihydroxy-4-pregnene-3,20-dione
CAS Number: 50-22-6
Molecular Weight: 346.46
Molecular Formula: C21H30O4
Purity:99.0%
Appearance: White to tan crystalline powder
Physical State: Solid
Solubility: Soluble in acetone, methanol, ethanol (10 mM), chloroform, and DMSO (100 mM). Insoluble in water.
Application: Corticosteroid is an activator of MCR
Storage: Store at room temperature
Description：
Corticosterone is a hormone synthesized in response to stress. It binds and activates MCRs(mineralocorticoid receptors) and GRs (glucocorticoid receptors), which results in altered expression. This eventually affects ionic conductances through the membrane. Corticosterone induces apoptosis in murine bone marrow.