Loratadine

Product name: Loratadine
CAS No.: 79794-75-5
Formula:C22H23ClN2O2
Mol. mass:382.88 g/mol
Appearance:
White crystals or crystalline powder
Use:
used to treat allergies. Structurally, it is closely related to tricyclic antidepressants such as imipramine
Product description:
Loratadine (INN) is a second-generation H1 histamine antagonist drug used to treat allergies. In terms of structure, it is closely related to tricyclic antidepressants, such as imipramine, and is distantly related to the atypical antipsychotic quetiapine.
Loratadine is marketed by Schering-Plough[needs update] under several trade names (e.g., Claritin) and also by Shionogi in Japan. It is available as a generic drug and is marketed for its nonsedating properties. In a version named Claritin-D or Clarinase, it is combined with pseudoephedrine, a decongestant; this makes it useful for colds as well as allergies but adds potential side-effects of insomnia, anxiety, and nervousness.