Mesna

Product name : Mesna

CAS : 19767-45-4

Molecular Formula : C₂H₅NaO₃S₂

Molecular Weight : 164.181

Product Description :
Mesna (INN) (pronounced /?m?zn?/) is an adjuvant used in cancer chemotherapy involving cyclophosphamide and ifosfamide.

Uses :
As a chemotherapy adjuvant
Mesna is used therapeutically to reduce the incidence of haemorrhagic cystitis and haematuria when a patient receives ifosfamide or cyclophosphamide for cancer chemotherapy. These two anticancer agents, in vivo, may be converted to urotoxic metabolites such as acrolein.
Other
Outside North America, mesna is also used as a mucolytic agent, working in the same way as acetylcysteine; it is sold for this indication as Mistabron and Mistabronco.

Mechanism : It is believed to act as an antioxidant.