Mycophenolate Mofetil

Product name : Mycophenolate Mofetil

CAS : 128794-94-5

Molecular formula : C₂₃H₃₁NO₇

Product description :
Mycophenolate mofetil (MMF) is an immunosuppressant and prodrug of mycophenolic acid, used extensively in transplant medicine. Its mode of action is as a reversible inhibitor of inosine monophosphate dehydrogenase(IMPDH) in purine biosynthesis. MMF is selective for the de novo pathway critical to lymphocytic proliferation and activation. Other cells are able to recover purines via a separate, scavenger, pathway and are thus able to escape the effect. It is a useful alternative to azathioprine when Aza toxicity precludes use.

CellCept is also used in the treatment of autoimmune disorders in which the immune system is overactive - such as Beh?et's disease and pemphigus vulgaris. Suppressing the immune system inhibits the body from attacking healthy cells (which a faulty immune system has labeled as a pathogen), thus preventing flares and complications from the disease. As with all immunosuppressants, a negative side effect of CellCept is that it weakens or eliminates the body's ability to defend itself against genuine pathogens, leaving the patient susceptible to infection.