Pomalidomide

Product name : Pomalidomide

CAS : 19171-19-8

Molecular formula : C₁₃H₁₁N₃O₄ 

Molecular Weight : 273.24

Product description :
Pomalidomide (originally CC-4047), is a derivative of thalidomide and acts as an immunomodulator. It can be taken orally.Phase I trial results showed neutropenia was a frequent side effect.Phase II clinical trials for multiple myeloma and myelofibrosis have reported 'promising results'.

Mechanism :
The immunomodulatory effect is probably due to inhibition of TNF-alpha. In vitro it affects erythropoeisis. and enhances antibody-dependent cellular cytotoxicity (ADCC).