Romiplostim

Product name : Romiplostim

CAS : 267639-76-9

Molecular formula : C₂₆₃₄H₄₀₈₆N₇₂₂O₇₉₀S₁₈

Product description:Romiplostim (rINN, USAN) is a fusion protein analog of thrombopoietin, a hormone that regulates platelet production. The drug was developed by Amgen and is marketed under the trade name Nplate through a restricted usage program called NEXUS.During development and clinical trials the drug was called AMG531.

Romiplostin is indicated as a potential treatment for chronic idiopathic (immune) thrombocytopenic purpura (ITP). Romiplostim was designated an orphan drug by the U.S. Food and Drug Administration (FDA) in 2003, as the chronic ITP population in the USA is under 200,000 (the chronic adult ITP population in the USA is thought to be around 60,000, with women outnumbering men by a factor of two).The wholesale cost of romiplostim if administered weekly is currently estimated at US $55,250 per year.