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Sotalol
Product Name : Sotalol
CAS : 3930-20-9
Molecular Formula : C12H20N2O3S
Molecular Weight : 272.3624
Product Description :
Sotalol (trade names Betapace and Betapace AF, Berlex Laboratories, Sotalex and Sotacor, Bristol-Myers Squibb) is a drug used in individuals with rhythm disturbances (cardiac arrhythmias) of the heart, and to treat hypertension in some individuals.
Sotalol is a non-selective beta blocker. It is also a potassium channel blocker and is therefore a class III anti-arrhythmic agent. Because of this dual-action, Sotalol prolongs both the PR interval and the QT interval.
Indications :
Sotalol is used to treat ventricular tachycardias as well as atrial fibrillation. Betapace AF is specifically labeled for atrial fibrillation.
Some evidence suggests that sotalol should be avoided in the setting of decreased ejection fraction due to an increased risk of death.
It has also been suggested that it be used in the prevention of atrial fibrillation.
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