Tranilast

Product name: Tranilast
CAS No.: 53902-12-8
Molecular Formula: C18H17NO5
Molecular Weight: 253.26
Solubility: Soluble in DMSO (>10 mg/ml), water (<1 mg/ml), and ethanol (<1 mg/ml).
Storage: Store at room temperature
Product description:
Tranilast is an anti-asthma drug, which inhibits LTC4 and PGE2 formation in stimulated monocytes, but does not inhibit cyclooxygenase or lipoxygenase activity; inhibits mast cell degranulation; inhibits VEGF-induced angiogenesis in vivo and also inhibits proliferation and tube formation of human endothelial cells in vitro. Tranilast may represent a new class of drugs for therapy to treat ongoing TH1-mediated autoimmune diseases.